Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (13): 2028-2033.doi: 10.3969/j.issn.2095-4344. 2015.13.012

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Risk factors for dysphagia after single-level anterior cervical fusion

Chen Bo1, Qu Xia2, Yang Yi1, Wang Kun1, Xie Chong1, Jin Ge-le1   

  1. 1Second Sickroom Section, Department of Surgery (VIP), the First Affiliated Hospital, Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China; 2Department of Nephropathy, Hospital of Traditional Chinese Medicine Affiliated to Luzhou Medical College, Luzhou 646000, Sichuan Province, China
  • Received:2014-12-30 Online:2015-03-26 Published:2015-03-26
  • Contact: Jin Ge-le, M.D., Professor, Chief physician, Second Sickroom Section, Department of Surgery (VIP), the First Affiliated Hospital, Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China
  • About author:Chen Bo, Studying for master’s degree, Second Sickroom Section, Department of Surgery (VIP), the First Affiliated Hospital, Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China
  • Supported by:

    the National Natural Science Foundation of China, No. 81301336

Abstract:

BACKGROUND: Dysphagia is one of common early complications after anterior cervical fusion. Medium and severe dysphagia often causes serious influence on the patients. A variety of factors have been shown to have a correlation with the postoperative dysphagia, but specific mechanism is still unclear.
OBJECTIVE: To explore the risk factors for dysphagia after single-level anterior cervical fusion.
METHODS: From January 2011 to June 2013, data of 44 patients with dysphagia and 213 patients without dysphagia after single-level anterior cervical fusion were compared. The baseline data (age, gender, ethnicity, body mass index, smoking history, drinking history, hypertension, diabetes, course length, and type of cervical spondylosis) and perioperative data (intraoperative blood loss, internal fixation, the location of the operated level, operation time, and the side of operation approach) between two groups were compared by Logistic regression analysis to determine risk factors for postoperative dysphagia.
RESULTS AND CONCLUSION: A total of 257 patients were included with a follow-up for 6 to 24 months postoperatively and 44 of them suffered from dysphagia after single-level anterior cervical fusion. The overall  prevalence for postoperative dysphagia was 17.1%. Univariate analysis indicated that age, gender, the location of the operated level, and course length were associated with postoperative dysphagia. Logistic regression analysis of multivariate analysis demonstrated that independent predictors for postoperative dysphagia included gender (female), age (> 60 years), the location of the operated level (C4-5, C5-6), and course length (> 12 months). Clinicians should give appropriate recognition and take corresponding measures to avoid it.


中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程


全文链接:

Key words: Cervical Vertebrae, Spinal Fusion, Postoperative Complications, Deglutition Disorders

CLC Number: